Low Dose Naltrexone (LDN) is being used as a regulator of the immune system, providing relief to patients with autoimmune diseases, and central nervous system disorders. Whilst it is not licensed by the FDA specifically for these conditions, physicians are permitted to prescribe LDN ‘off-label’ for treatments they think are appropriate.
The apparently diverse conditions in which LDN appears to have a therapeutic effect are united by their ability to benefit from increased levels of endorphins (naturally occurring opioids – specifically OGF).
In the interests of promoting further research into different uses of LDN, we encourage LDN users who are willing to be identified to share their experiences with LDN by clicking on Submit Your Story.
Examples of the successful use of LDN, supported by studies as well as reported by patients to date, include the following conditions:
- Alcoholism
- Amyotrophic Lateral Sclerosis (ALS)
- AutoImmune (general)
- Cancer (general)
- Chronic Pain
- Covid-19
- Crohn's Disease
- Depression
- Diabetic Neuropathy
- Dissociative Disorder
- Fibromyalgia
- Glioma
- Gulf War Illness
- HIV
- Hyperinsulinemia
- IBD
- IBS
- Lichen Planopilaris
- MS (Multiple Sclerosis)
- Parkinson's
- Psoriasis
- Psychiatric Conditions
- PTSD
- Ulcerative Colitis
- Adenoid Cystic Carcinoma
- Amyopathic Dermatomyositis
- Ankylosing Spondylitis
- Autism Spectrum Disorder
- AutoImmune (general)
- Bipolar
- Burning Mouth Syndrome
- Cancer (general)
- CFS
- Cholangiocarcinoma
- Chronic Pain
- Colon Cancer
- Constipation (chronic)
- Crohn's Disease
- CRPS
- Darier Disease
- Depression
- Dermatitis Herpetiformis
- Dermatomyositis
- Diabetic Neuropathy
- Ehlers-Danos syndrome
- Endometrial Intraepithelial Neoplasia
- Epilepsy
- Erythmodermic Psoriasis
- Erythromelalgia
- Esophageal Carcinoma
- Fibromyalgia
- Hailey-Hailey
- Hepatoblastoma
- hepatocelluar carcinoma (HCC)
- Hepatocellular Carcinoma
- Hypothyroidism
- IBD
- IBS
- Interstitial Cystitis
- Lichen Planopilaris
- Liver Cancer
- Lung Cancer
- Lupus
- Lymphoma
- MCAS (mast cell activation syndrome)
- Mesenteric Panniculitis
- Migraine
- MS (Multiple Sclerosis)
- Neuropathic Corneal Pain
- OIH (Opioid Induced Hyperalgesia)
- Ovarian Cancer
- Pancreatic Cancer
- Parotid Carcinoma
- POTS (postural orthostatic tachycardia)
- Prostate Cancer
- Pruritus
- Psoriasis
- Psychiatric Conditions
- Renal Cell Carcinoma
- Rheumatoid Arthritis
- Sarcoidosis
- Seropositive Arthritis
- Sjogren’s
- SPS (Stiff Person Syndrome)
- Systemic Sclerosis
- Transverse Myelitis
- Ulcerative Colitis
- Uterine Sarcoma
- Allergies
- Anxiety
- Arthritis
- AutoImmune (general)
- Cancer (general)
- CFS
- Chronic Back Pain
- Chronic Pain
- Crohn's Disease
- Depression
- Fibromyalgia
- Grave's Disease
- Hashimoto's
- Hepatitis C
- Hypertension
- Hypothyroidism
- IBS
- Interstitial Cystitis
- Lung Cancer
- Lupus
- Lyme Disease
- MS (Multiple Sclerosis)
- Myasthenia Gravis
- Osteoarthritis
- Parkinson's
- PPS (Post-Polio Syndrome)
- Psoriasis
- Psoriatic Arthritis
- Raynaud's
- Reactive Hypoglycemia
- Restless Legs Syndrome
- Rheumatoid Arthritis
- Sinusitis
- Sjogren’s
- Ulcerative Colitis
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