Find us on:

LDN is a specialty medication meaning it’s custom-prepared by compounding pharmacies or “specials pharmacies” using the approved drug - naltrexone - but in a specially formulated way. Unlike medications in which ingredients and production processes are standardized, the formulation and quality of LDN will depend on the pharmacy that produces it.

LDNscience has compiled helpful guidance that explains the difference between LDN formulations and what you should look out for. Knowledge is power, and will enable you to make good LDN decisions.

LDN Buyer

The Different LDN Formulations


Benefits: Easy to swallow
Drawbacks: Cannot be cut
Storage: Room Temperature
Cautions: Avoid fillers/excipients that slow down release
Avoid lactose for people with lactose sensitivity


Benefits: Ease of swallowing
Sometimes are scored so can be divided into smaller doses
Drawbacks: More excipients (fillers) than capsules
Storage: Room Temperature
Cautions: Avoid fillers/excipients that slow down release
Avoid lactose for people with lactose sensitivity

Liquid / Drops

Benefits: Fastest absorption
Can be mixed into liquids. Allows very small dose modifications
Drawbacks: Short stability for some formulations
Can have a bitter taste if placed directly in mouth
Storage: Refrigerated or room temperature - follow the pharmacy’s storage instructions
Cautions: Pay attention to short expiration dates

Important Other types of naltrexone formulations are available for other purposes. While these can have medical benefits, these formulations should not be confused with the regular well-studied “low dose” naltrexone (LDN).

  • Slow-release or Extended-release: Such formulations should be avoided because they prevent the necessary rebound effect that makes low dose naltrexone effective.
  • Cream: Since creams are absorbed slowly through the skin, they don’t provide the typical “rebound effect” necessary for low dose naltrexone to work.

Know about Fillers

A filler is an inactive ingredient that is mixed with naltrexone in order to ensure uniform filling and dosing. Certain fillers may physically bind with the LDN which prevents its necessary rapid absorption. Here is what you should know:

  • Cellulose or plant-fiber fillers are more likely to bind with the LDN and slow its absorption. They are best avoided.
  • Protein-based fillers (amino acids such as glycine) do not slow down LDN absorption.
  • Simple-sugar fillers such as sucrose, dextrose, or lactose do not slow down LDN absorption.
  • Lactose should be avoided by individuals with lactose intolerance, gastrointestinal issues, irritable bowel syndrome (IBS), inflammatory bowel disease (IBD, such as Crohn’s and Colitis), and leaky gut syndrome.
  • Propylene glycol (also known as methylethylene glycol), and glycerine are suitable for use in liquid LDN formulations.

Choose the Best Pharmacy For You

To find the right compounding pharmacy to prepare your LDN, a great start is to look at LDNscience’s free global compounding pharmacy directory. It is an excellent resource to find a pharmacy closest to you that is familiar with LDN preparation. You can discuss with them (in addition to your LDN prescriber) what formulation and fillers would be best for you. By following these steps, you can ensure that your LDN experience is as optimal as can be.

weight loss: essential oil for weight loss track my weight loss cannot loss weight acaiberry weight loss enema for weight loss low sugar diet weight loss plan candida and weight loss sodas and weight loss does wellbutrin help with weight loss weight loss games for groups kaiser weight loss programs diabetes weight loss diet plan mexico weight loss surgery reviews keto burn pills shark tank faster way to weight loss weight loss retreats for adults affordable weight loss xenadrine weight loss reviews dr pasternack weight loss weight loss pills popular does phentermine work for weight loss ovasitol weight loss dr rouhana weight loss weight loss pills safe for pregnancy do b12 shots work for weight loss best natural diet for weight loss sota weight loss price compression weight loss weight loss clinic hazard ky natural appetite suppressant pills stomach fat weight loss pills tessa brooks weight loss weight loss on paleo diet top diet pills sold in stores where can i buy ace diet pill tone fire forskolin

vape: 150w vape mods denali vapor vape vibe johnstown smok nord wont turn on vuse alto charger 150 watt box mods le 80 box mod vape cbd oil vapor 99 xeo void vape pen vapor station near me pegasus ecig mod nike vapor 360 gloves dangers in vaping watermelon ice vape juice used vape mods for sale prefilled cartridges e cigarette used voopoo mods is vaping fda approved smok t storm mod firmware update how many ml of nicotine in a cigarette steampunk vape mod for sale mini vape starter kit vape shops in lafayette la long lasting 18650 vape battery ajs vapor cloud king 18650 how to get a nicotine buzz from vaping best coffee e juice 2018 ijoy combo sense herakles manual different uwell crown coils uwell crown tank youtube imperial vape uwell ceramic report sigelei 200w kit

cbd oil: topical cbd oil high cbd autoflower seeds cbd oil anchorage water soluble cbd oil brands green mountain cbd reddit cheapest cbd vape oil joy organics cbd price best cbd dropshippers how long does cbd oil last in the fridge cbd vape pen cartridges cannabinoid thyroid does cbd show up on a drug screen cannabis oil cures extract cbd cannabinoid opioid interaction in chronic pain jeweller brisbane cbd tera codes just vapes is cbd oil legal in ohio august 2019 cannabis oil cancer snopes cbd for dental pain no xplode side effects cbd illegal in california cbd e liquid under tongue does cbd help anxiety coupon for plus cbd oil epidiolex side effects can i take cbd oil with lisinopril cbd distilley oil review cbd oil advantage cbd ratio tincture how many mg do i want in cbd oil to help with sesers pure cbd oil south africa benefits of cbd oil for seniors cbd hemp direct promo code

male enhancement: sex drugs how long does your penis grow for pump pills can you take cialis with food remedy for erectile dysfunction penis tip sore jelly dick what drug is this online pain pills erection cream that works viagra super active review penis pump before and after jelqing cream promo code for romans penis circumference how to make viagra work faster avg penis girth adderall and viagra how big is the average size penis levitra alternative different kinds of dicks a large penis progentra does it work micro penis erection rhino male enhancement amazon revboost review men with ed penis cap primal sexuality measuring penis size t booster side effects substitute for viagra enzene male enhancement 5 white pill big jim pills ed treatments