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Q & A: What Else Do I Need To Know About LDN?

Ultra-Low Dose Naltrexone is typically less than 10% the amount of an LDN dose, sometimes much less. Low dose Naltrexone is generally considered to be a range between 1 to 10 milligrams (the most typical dose being 4.5mg), while ultra-Low Dose Naltrexone is 0.1 to 0.2 milligrams (but has been studied in much smaller amounts). There have been studies showing that ultra-Low Dose Naltrexone taken together with (at the same time as) opioids can enhance the pain-relieving effect of opioids and reverse some negative side effects of opioids. However, ultra-Low Dose Naltrexone is a separate treatment approach than Low-Dose Naltrexone, so LDNscience.org (which is dedicated to the science of LDN) does not deal extensively with this topic. To find out more information about ultra-Low Dose Naltrexone, one should seek out the specific resources that deal with that topic.
While they sound similar, they are not the same drug. They both belong to the same family of drugs, but their function is different. Their differ in the length of time and extent to which they block opioid receptors. The hundreds of studies on LDN used naltrexone, not naloxone.

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