Find us on:


Immuno-regulatory effects on murine macrophages by low dose naltrexone (LDN)

Immuno-regulatory effects on murine macrophages by low dose naltrexone (LDN)
Publication Type
Journal Article
Research Type
Lab (in-vitro)
Reported as
January 28, 2016
Sheng-Nan Guo, Yan Li, Xiao-Nan Wang, Feng-Ping Shan
China Medical University

OBJECTIVE: The effect of naltrexone on the function of murine peritoneal macrophages in vitro was studied in order to illuminate its immune activity further.

METHODS: Peritoneal macrophages were divided in three groups: RPMI1640 blank control group, LPS positive control group and NTX treated group. Various phenotypic and functional indices were tested by MTS, flow cytometry technology, phagocytosis experiment and ELISA.

RESULTS: Compared with the RPMI1640 group, LDN exhibited paradoxical properties; the expression of CD64 on the surface increased while the expression of CD206 decreased in the NTX group; the expression of tumour necrosis factor-α (TNF-α), interleukin-6 (IL-6), interleukin-1β (IL-1β) were increased.

CONCLUSION: The results of the experiment proved that LDN could influence macrophage polarization, regulate inflammatory mediator production and affect the phagocytic function of peritoneal macrophages.

cbd oil: smoking cbd oil pros of cbd oil authentic cbd oil eppendorf research plus disposable cbd vape cbd oil users group facebook cbd oil just chill cbd and parkinsons video full spectrum cbd oil zero thc cbd products near me water soluble cbd tincture cbd whole sale can you buy cbd in texas bigcommerce ecommerce platforms cbd dealers eye vitamins amazon best tank for cbd oil price of cbd oil savage cbd oil 1000mg cbd oil spray review nj weed legalization date cbd edibles austin p38 gene nbc 6 cbd oil the definition of reason does cbd oil help trigeminal nerve pain cbd melting point free cbd vape oil sample marijuana testosterone cbd oil order online google health insurance plan does marijuana thin your blood real yeezy 750 boost cbd and sex cannabidiol boiling point doterra university terra international canada hemp bombs cbd vape juice herbal plus products arthritis cream omnitrition mct cbd oil cbd melbourne fl cbd oil pocatello idaho metabolic regulation definition does pure spectrum cbd oil vape help you sleep hemp vs marijuana cbd cbd oil to rub on not eat cheapest high potency cbd vape oil

weight loss: yoga and weight loss is hot sauce good for weight loss prescription weight loss injections quick weight loss fast sex and weight loss steam room weight loss raisins weight loss how well does alli diet pills work alexis bledel weight loss weight loss no alcohol latest weight loss news 17 day diet weight loss results gaba weight loss lexi and danny weight loss dinitrophenol weight loss pills weight loss crystal medi weight loss wayne nj weight loss pills with the best results weight loss clinic houston carb intake calculator for weight loss magnesium benefits for weight loss good diet supplements loss weight paleo diet weight loss one month david goggins weight loss diet diabetes pill for weight loss how to make a meal plan for weight loss soft drinks and weight loss no meat for 30 days weight loss nutritious smoothies for weight loss rowing before and after weight loss 8 week weight loss meal plan flabby skin after weight loss prescription weight loss pills qsymia medi weight loss forum chinese weight loss pills 2014 healthy grocery list for weight loss weight loss pills slimquick 1200 calorie meal plan for weight loss diet pills from china acie berry weight loss master diet pills weight loss success stories 2017 top lose weight pills fda approved weight loss drug low carb diet menu plan weight loss menopause weight loss natural remedies clean diet plan for weight loss matt damon martian weight loss

male enhancement: medic sex fenugreek vitamin shoppe indian viagra brands man 1 oil review cialis 5mg reviews penis pump results what is a big penis boner cocktail dick exercise alphaviril gnc how to make dick grow force fit xl penile girth penis enlargement weights how to get bigger pennis naturally bloody ejaculations my boyfriends cock is too big vitamins to restart puberty tiny erection virile male enhancement average white penis length penis enlargement excercise male sexual enhancement products what makes a woman good in bed what is the average penile size aloe vera for male enhancement red rhino pill reviews gnc testosterone supplement brahma male enhancement reviews ageless male supplement pmma penile injection whats considered a big dick average cost of penile implant natural ways to make dick bigger tax dollars pay for viagra small erect penis pictures medlineplus drugs alfuzosin interactions get viagra without doctor red itchy bumps on penile shaft minoxidil price sildenafil 50 mg online alpha testo max l arginine reddit alpha fuel xt review allergy medicine comparison brain supplements review foreskin sex

vape: celebrities who vape liquid vapor phase diagram mocha vape juice quality vape box vape pen vs juul evod 4 in 1 vape pen flavors of vape e cig vapor juice obs cube crown uwell metallic flavor cigar n vape dangers of vape pens giant vapes coupon 3mg nicotine e juice voltage smoke shop anti anxiety vape juice vapors without nicotine smok stick v8 manual pdf keystone vapor maui waui vape juice mercury vapor pressure e cig that taste like a cigarette without pg ecig videos vaping zone columbia sc blueberry pomegranate vape juice 2 ohms vape vaping on college campuses crown by uwell coils aspire nautilus x kit how much is the e cigarette industry worth voopoo drag problems aurora play vape smok tfv4 sextuple coil hybrid mech rda vape guide criss cross vape juice mystica vape review medical marijuana vape pen smok tf rta g2 best dank vape flavors uwell crown tank clone art of vaping uwell crown rafale reddit snoop vape pens super voopoo genevape vape how to voopoo custom themes best variable voltage ecig