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In patients with fibromyalgia, is low-dose naltrexone effective in alleviating pain, and does it decrease use of oral opioids?

Title
In patients with fibromyalgia, is low-dose naltrexone effective in alleviating pain, and does it decrease use of oral opioids?
Publication Type
Journal Article
Research Type
Human
Reported as
Review
Date
June 01, 2017
Authors
Sheryl Beard & Lary Hill
Institution
University of Kansas School of Medicine at Wichita
Link
Abstract

In patients with fibromyalgia, is low-dose naltrexone effective in alleviating pain, and does it decrease use of oral opioids? Evidence-based answer: Used alone, low-dose naltrexone modestly reduces pain compared with placebo. No studies have addressed the effect of low-dose naltrexone on oral opioid use in patients with fibromyalgia.