Find us on:

Research

Management of Pediatric Complex Regional Pain Syndrome with Low-Dose Naltrexone

Title
Management of Pediatric Complex Regional Pain Syndrome with Low-Dose Naltrexone
Publication Type
Journal Article
Research Type
Human
Reported as
Case Report/Series/Restrospective Study
Date
May 01, 2021
Authors
Amol Soin
Institution
Wright State University
Link
Abstract

BACKGROUND: Complex regional pain syndrome (CRPS) is a chronic, orphan neurologic condition that affects the extremities after nerve trauma or injury. Management of CRPS can be challenging due to a paucity of evidence surrounding treatment options. Low-dose naltrexone (LDN) has been used for the management of other types of chronic pain. LDN is believed to exert its activities through inhibition of Toll-like receptor 4, which attenuates microglial activation. This case report describes the use of LDN in an 11-year-old boy with CRPS.

CASE REPORT: Prior to initiating LDN, this patient was treated with gabapentin and amitriptyline, which were associated with undesirable adverse effects. Initiation of LDN allowed for successful discontinuation of gabapentin and amitriptyline. With LDN treatment, the patient’s pain severity improved by 70%, and self-reported functional status improved by 60%.

CONCLUSION: This case report adds to the growing body of evidence that suggests LDN is an effective treatment for chronic pain.

modere weight loss average weight loss with metformin weight loss app foods that aid weight loss qvc leah williams weight loss surgery quick healthy weight loss diet honey boo boo weight loss 2017 wellbutrin weight loss reddit grapefruit weight loss drink 40 day daniel fast weight loss atomic weight loss pill keiynan lonsdale weight loss lena dunham weight loss photos superfoods diet pills weight loss essay white pearl diet pills honey boo boo mom weight loss 2016 customer reviews weight loss pills type 2 diabetes injections weight loss weight loss pills safe for teenagers 15 day weight loss support best salad for weight loss 3 smoothies a day weight loss mama june weight loss photos final trim weight loss pills free trial is herbalife good for weight loss diet pills definition water diet for weight loss relacore diet pills reviews can depression cause weight loss alpha diet pills quick weight loss protein bars who sells adipex diet pills apple cider vinegar weight loss kris jenner weight loss diet diet food for weight loss garcinia burn where to buy jacob miller weight loss

lost my sex drive vitamin d libido does birth control lower your sex drive small limp dick over the counter ed pills at walmart stay hard longer pills the best erectile dysfunction pills foods that cure ed natural cures pulmonary hypertension what does a percocet look like lasting erection htx male enhancement reviews vigorous male enhancement estrogen blocker reviews lab penis pe bible results pictures where can i get viagra over the counter malexl pills red pills for uti woman viagra what can cause 4929 pill not getting full erection red male enhancement pill embarassing erections upper arm cuff gold pandora god of war bromelain pill gnc staminol review xyzal free trial sexual foods top brain supplements male penis pictures l arginine for ed hcg testosterone booster revboost where to buy diet pills that work men penises pictures

bulk cbd oil diarrhea marijuana medterra cbd tincture mediswift cbd oil cbd vape cartridge near me miracle gro liquid cbd dosage for lupus cbd and hemp oil difference american shaman water soluble cbd heady harvest cbd cbd oil drug interaction componente de la marihuana best liposomal cbd oil dont feel anything from cbd top cbd brands 2019 sugar free gummy bears reviews medicinal cannabis oil for sale closest spectrum office best strains for pain and fatigue willie nelson vape how to make cannabinoid oil phytocannabinoids vs cannabinoids relax a liquid mind experience property to rent in johannesburg cbd jl powell coupon codes will cbd oil show up on a urine test what time 99 cent store close gwu health insurance cbd oil and how it works amount def cbd oil and mucus 20 mg of cbd hemp honey cbd oil reviews cbd oil galesburg il 1000 mg cbd oil to treat cancer cbd 831 salinas 300mg cbd oil review how to take cbd oil for osteoporosis

vape no A Tag