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Research

Naltrexone Hydrochloride 1.5-mg and 4.5-mg Capsules

Title
Naltrexone Hydrochloride 1.5-mg and 4.5-mg Capsules
Publication Type
Journal Article
Research Type
Human
Reported as
Review
Date
March 19, 2020
Authors
Loyd V. Allen, Jr., PhD
Institution
University of Oklahoma
Link
Abstract

Pharmacist Dr. Loyd V. Allen, Jr. reviews methods of preparation, uses, packaging, labeling, stability, and quality control of 1.5mg and 4.5mg capsules of low dose naltrexone. An interesting and unexpected effect of naltrexone is its action in pain relief for different disorders. A notable aspect of naltrexone use in pain patients is that the dose is only about one-tenth of the normal dose. Since naltrexone HCl is available in 50-mg tablets, low-dose naltrexone must be compounded for patients.