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Research

Low-Dose Naltrexone for disease prevention and quality of life

Title
Low-Dose Naltrexone for disease prevention and quality of life
Publication Type
Journal Article
Research Type
Human
Reported as
Opinion
Date
January 01, 2009
Authors
Brown N, Panksepp J.
Institution
Embry-Riddle Aeronautical University
Link
Abstract

The use of Low-Dose Naltrexone (LDN) for the treatment and prophylaxis of various bodily disorders is discussed. Accumulating evidence suggests that LDN can promote health supporting immune-modulation which may reduce various oncogenic and inflammatory autoimmune processes. Since LDN can upregulate endogenous opioid activity, it may also have a role in promoting stress resilience, exercise, social bonding, and emotional well-being, as well as amelioration of psychiatric problems such a autism and depression. It is proposed that LDN can be used effectively as a buffer for a large variety of bodily and mental ailments through its ability to beneficially modulate both the immune system and the brain neurochemistries that regulate positive affect.