Find us on:

Research

Low Dose Naltrexone in the Treatment of Fibromyalgia

Title
Low Dose Naltrexone in the Treatment of Fibromyalgia
Publication Type
Journal Article
Research Type
Human
Reported as
Case Report/Series/Restrospective Study
Date
March 17, 2017
Authors
Samy K Metyas, Karen Yeter, John Solyman, Daniel Arkfeld
Institution
University of Southern California and Covina Arthritis Clinic
Link
Abstract

Fibromyalgia is a chronic pain disorder characterized by diffuse musculoskeletal pain, fatigue, sleep disturbance and cognitive impairment. A significant number of fibromyalgia patients do not respond adequately to the current drugs (pregabalin, milnacipran, duloxetine) approved for fibromyalgia treatment by the Food and Drug Administration (FDA). Thus, there is still a need for adjunctive therapies. Naltrexone is an opioid receptor antagonist used to treat alcohol and opioid dependence. It is hypothesized that low dose naltrexone causes transient blockade of opioid receptors centrally resulting in a rebound of endorphin function which may attenuate pain in fibromyalgia. Treatment with low dose naltrexone may be an effective, highly tolerable and inexpensive treatment for fibromyalgia. Further controlled trials are needed.

weight loss: diabetes and weight loss weight loss due to diabetes compass weight loss state of the art weight loss cost orlistat weight loss cryotherapy weight loss side effects low impact exercise for weight loss chef aj ultimate weight loss reviews apple vinegar weight loss drink methotrexate and weight loss pills fiber powder for weight loss weight loss for menopause weight gain paleo weight loss stories topamax weight loss dosage loss weight pills reviews anderson cooper weight loss gnc release diet pills best weight loss pills no caffeine leptovox diet pills quick weight loss boca raton aliduet diet pills diabetes weight loss meal plan cheryl burke diet pills calorie diet pills super hd diet pills reviews fahrenheit diet pills website protein bar diet weight loss piperine weight loss paleo diet plan for weight loss indian adipex weight loss pill

vape: vandy vape pulse x bf 90w starter kit diy vape flavoring vape pen how to rhythm vape pen itaste mvp high wattage box mod gorilla glue vape cheap e cigarette juice what does strength mean in vape juice dark chocolate vape juice e cigarette coughing vaping with a ccell smoktech priv v8 rain city vape just vapes smok mag 225w how to turn on v8 baby coils vapor 10xt rba tank reviews vape burn nano vape tank can minors vape king tank vape pen no nicotine fancier tank uwell smok spirals tank review screen for uwell crown tank best vape pen nicotine voopoo volt battery package luci ecig

cbd oil: cbd vape juice amazon vitamins cbd american shaman get you high xterra body armor fresh thyme cbd kalki cbd oil reviews what does cbd vape oil do is clear cbd oil good best restaurants sydney cbd relax gummies cbd cbd oil to treat cancer cbd pharmacokinetics hemperor beer cbd can you mix cbd oil with a drink recovery cbd cheapest cbd oil drops thc stands for personal trainer perth cbd huntingtons disease online cbd what does it mean when delta g is negative kigh cbd type b thymoma cbd health of indiana cbd 43 remedy cbd oil dosage for anxiety cbd oil allergy where to buy cbd in tucson migraine and cbd oil fact sheets

male enhancement: loss of sexual desire penis tissues best pills for sex primal male xl how to buy pain pills online how to make a woman want sex can you really make your penis bigger herbs that help diabetes fat around penis zyntix male enhancement pills cock growth gif how to overcome erectile dysfunction make penis smaller a mans dick when do guys feet stop growing how to use penis pumps how to get viagra without a doctor free viagra sample niacin dosage for ed adding girth to penis seroquel erectile dysfunction vegetarian testosterone boosters black guy booty pill 5880 fun facts about penis want your sex white 223 pill prescription drug name semen amount doctor checks penis