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Variable Response to Naltrexone in Patients With Hailey-Hailey Disease

Title
Variable Response to Naltrexone in Patients With Hailey-Hailey Disease
Publication Type
Journal Article
Research Type
Human
Reported as
Case Report/Series/Restrospective Study
Date
January 17, 2018
Authors
Severine Cao; Evelyn Lilly; Steven T. Chen
Institution
Harvard Medical School; Massachusetts General Hospital
Link
Abstract

Hailey-Hailey disease (HHD) is a genetic intraepidermal blistering disorder characterized by chronic macerated erosions in intertriginous areas. The recent report of 2 case series demonstrating the efficacy of low-dose naltrexone in the treatment of HHD represents exciting progress in the management of a disease with limited therapeutic options. Herein we present 3 additional cases of HHD demonstrating varying responses to naltrexone.