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Sjogren's Syndrome: Clinical Benefits of Low-dose Naltrexone Therapy

Sjogren's Syndrome: Clinical Benefits of Low-dose Naltrexone Therapy
Publication Type
Journal Article
Research Type
Reported as
Case Report/Series/Restrospective Study
March 11, 2019
Scott Zashin
University of Texas Southwest Medical Center

Sjogren’s Syndrome is a chronic autoimmune disorder that causes the inflammation of the lacrimal and salivary glands, resulting in dryness of the eyes and mouth. In addition, fatigue and musculoskeletal pain, often described as aching, is very common. Treatment directed toward alleviating the fatigue and pain associated with Sjogren’s is currently very limited. This report describes a case of a 47-year-old female with suspected Sjogren's based on long-standing dry eyes, dry mouth, joint pain, fatigue, elevated measures of inflammation, and a positive rheumatoid factor. She failed standard therapy but improved clinically with low-dose naltrexone therapy.

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