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Interviews with Experts

Dr. Amol Soin
August 01, 2021
LDN for CRPS: FDA Orphan Drug Designation and Beyond
Interview with Dr. Amol Soin, pain management specialist affiliated with Wright State University and medical director of the Ohio Pain Clinic
After Dr. Amol Soin saw remarkable results using LDN to treat a pediatric patient with intractable Complex Regional Pain Syndrome (CRPS), he began prescribing LDN to many of his patients with CRPS, seeing significant symptomatic improvement in each one. Dr. Soin published a case report about the pediatric patient, published a comprehensive literature review study of LDN for pain, and received FDA orphan drug designation for LDN in CRPS. He shares with LDNscience his observations about LDN and the future LDN research he hopes to conduct.
Dr. Scott Zashin
November 20, 2019
LDN for Sjögren's Syndrome
Interview with Dr. Scott Zashin, rheumatologist and internist affiliated with the University of Texas
Dr. Scott Zashin published the first peer-reviewed article about a patient with Sjögren's Syndrome who responded to low dose naltrexone. Dr. Zashin shared his experience about that patient, and the subsequent Sjögren's patients that he has treated with LDN. He shares his observations about LDN, and discusses future projects he hopes to be involved in.
Dr. Leonard Weinstock
June 10, 2019
LDN for Psoriasis and Psoriatic Arthritis
Interview with Dr. Leonard Weinstock, President of Specialists in Gastroenterology, and Associate Professor of Clinical Medicine and Surgery at the Washington University School of Medicine
Dr. Leonard Weinstock shares remarkable new cases of LDN successfully used for psoriasis and psoriatic arthritis. He describes the almost total resolution of psoriasis, psoriatic arthritis, and IBS, of one of his patients. Dr. Weinstock also discusses the high response rate among 15 patients with psoriasis who were treated with LDN, and what message we should take from this finding.
Dr. Guttorm Raknes
April 15, 2019
LDN for Rheumatoid Arthritis
Interview with Dr. Guttorm Raknes of the University Hospital of North Norway and Raknes Research
Guttorm Raknes, M.D., Ph.D. of the University Hospital of North Norway and Raknes Research, studies the impact of low dose naltrexone on the use of other medications among the Norwegian population. In this interview, Dr. Raknes discusses how the use of LDN among patients with rheumatic joint disease (such as rheumatoid arthritis) affected other medications they receive (such as painkillers and immunosuppressants). Dr. Raknes suggests that it's likely that long term use of LDN may help rheumatoid arthritis, and he hopes their study findings will encourage funding of LDN clinical trials.
Dr. Brian Johnson
April 03, 2019
LDN for Fibromyalgia
Interview with Dr. Brian Johnson of SUNY Upstate Medical University
As the Director of Addiction Psychiatry at SUNY Upstate Medical University, Dr. Brian Johnson studies pain and pain relief. He considers fibromyalgia to be an autoimmune version of opioid withdrawal, and suggests that both fibromyalgia and opioid withdrawal involve a dysregulation of the opioid system: low opioid tone. He discusses his research using low dose naltrexone to treat both disorders and how LDN therapy is a far superior treatment for treating fibromyalgia.
Dr. Wai Liu
January 19, 2018
LDN's Anti-Cancer Effects
Interview with Dr. Wai Liu of St. George's University of London
Dr. Wai Liu, an experienced cancer researcher at St. George’s University of London, researches novel cancer treatments, including modifications to established drug regimens to enhance the effectiveness of chemotherapy. His work includes studying the anticancer effects of low dose naltrexone (LDN), which he discusses in this interview with LDNscience.org.
Dr. Mark Shukhman
January 01, 2017
LDN's Surprising Effects on Sexual Dysfunction, Addiction and Mental Illness
Interview with Dr. Mark Shukhman of the Northshore University Health System/Private Practice
Dr. Mark Shukhman is a psychiatrist in private practice. He was introduced to LDN around 2011 and has been using it with his patients since then. In this interview, he describes his observations about how patients with sexual dysfunction, addictions of various kinds, and mood disorders are responding to LDN. He discusses his philosophy on when to take LDN, why he thinks LDN works for some patients better than others, and future research that he would like to do.
Dr. Guttorm Raknes
November 13, 2016
LDN transforms a country: Interview with health expert Dr. Guttorm Raknes
Interview with Dr. Guttorm Raknes of the University Hospital of North Norway and Uni Research Health
As an expert in repurposed drugs, Guttorm Raknes, M.D., Ph.D. of the University Hospital of North Norway and Uni Research Health, became extremely interested in low dose naltrexone when patient requests and prescription numbers suddenly skyrocketed. A television documentary reported patients' success with LDN which sparked this "overnight" interest. Dr. Raknes studied the phenomenon and published a report, hoping to encourage support from the Norwegian government to fund clinical trials.
Dr. Burton Berkson
May 01, 2016
Having a Choice: Successful Use of LDN for Difficult-To-Treat Cancers and AutoImmune Diseases
Interview with Dr. Burton Berkson of the Integrative Medical Center in Las Cruces, New Mexico, USA.
Dr. Burton Berkson, a highly accomplished integrative physician/researcher who first published about LDN, and combination LDN plus alpha lipoic acid, for pancreatic cancer and B-cell lymphoma, discusses what he has learned about LDN's benefits for a variety of conditions, including notoroiusly difficult-to-treat cancers and autoimmune diseases.
Dr. Phil Boyle
February 01, 2016
LDN's Impact on Infertility, AutoImmune Disease and Epigenetics
Interview with Dr. Phil Boyle, Director of the NaPro Fertility Care Clinic in Dublin, Ireland
Dr. Boyle shares his innovative approach using LDN for gynecological and obstetric disorders that are thought to have underlying deficiencies in endogenous endorphins that respond to LDN. He describes how he began trying LDN with his patients who had both difficulties with fertility and autoimmune disorders, and found LDN to improve both. Over the course of years, his use of LDN has expanded to thousands of patients, and has begun to theorize that, in the case of certain disorders (such as endometriosis and autism spectrum disorders), LDN during pregnancy may have a positive effect on the future health of the resulting children. Observations from clinical practice and directions for future research and clinical applications are described.

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